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1.
A term used in the D/s community for a submissive who's responsable for taking care of the home, cleaning up after play paries, and tending to any needs of the Dom.

A house mouse is usualy Not collared by the Dom they work under.

The payments and punishments of a good or badly done job are usualy defined by the Dom.
Master P has a cute lil house mouse, she'll get on her knees and scrub the floor - then polish his knob.
de QueerFemmeGirl 4 janvier 2007
 
2.
Usualy used in motorcycling circles, to describe a female of questionable virtue, who tends to drift from house to house; bed to bed; person to person. Often repeating themselves throughout the course of a year.

Or

A motorcycle groupy.
"So... your seeing so and so... eh"

"Yeah... I realy like her man."

"Well don't get to attached... she's a bit of a House Mouse... and Kevin just got a new Duc
de schimschone 12 mars 2005
 
3.
A snitch.
"Better move that fucking contraband. First Sergeant's house mouse just saw you shove it underneath there."
de Doc Soul 6 avril 2009
 
4.
Boobs, tits, breasts.
Damn, Molly has some nice house mouses!
de Jason B 13 mars 2003