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1.
To hit the bottle is to drink alcohol to the point of intoxication.
Brother 1: "Do you think Mom's gonna hit the bottle tonight?"

Brother 2: "Does a bear shit in the woods?"
de neutralmilkhotel 16 janvier 2006
 
2.
To acquire and drink alcohol, usually beer.
"My wife divorced me 'cause I wasn't making enough money. I was all depressed........yeah yeah, I know. I hit the bottle after all that shit. Who wouldn't!?"
de Dave 15 mai 2004