Top Definition
Refers to someone who is extraordinarily dumb, as exhibited by extraordinarily bad choices.

It just refers to someone who is exraordinarily dumb. A derivative of "dumbfucks" from the latin dummass frickinious idiotus.

Dude was a total duffus and used gasoline to start his charcoal for the picnic! Hence the fire department and paramedics
de DustyDude 3 juin 2015
Name for the worst people in existence, also name for vagina or something thats broken.
Duff: "My name is @##$ Duffus"
Bystandard: "How do you sleep at night"
de Patrick!@#$%%^^ 13 avril 2006
A long, thick, uncircumcised penis; The best sex any member of the female species could hope for.
That guy had quite the duffus!

I had some duffus last night..... it was phenomenal!
de imsothug 29 avril 2011

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