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1.
(drunkspeak) To one-up someone's one-up, or to severely one-up someone.
Soberguy- Always trying to one-up me, aren't you...
Drunkguy- I'll two-up you....
de atomicdonkey 14 février 2005
 
2.
Simoultaneous sex with a womans rear and front entry
Ooooh that must hurt!
de Rear entry Reg 19 novembre 2003
 
3.
a way of saying "peace", often used as a sign off or a symbol of one's departure. the name is derived from the two fingers that go up when making a peace sign with a hand.
Rick: "Remember that we gotta' pick up Susan tomorrow."
Bill: "Alright, man, i'll remember. I'm calling it a night. Two up."
de Kid Glorious 20 mars 2010