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1.
A sexual encounter involving tires. Similar to a threesome, but with tires.
Justin is chaffed and covered in friction burns from an erotic tiresome last evening.
de Phil Korn 5 novembre 2010
 
2.
Something that is so crazy or so hard that it makes you really tired.
Henry: Damn that party was tiresome last night.

Katie: I know. I woke up at noon after getting so hyper and crashing
de Henry (edumacated) 23 novembre 2008