Acronym of "Toughen the fuck up".
Dude No 1: I really dont feel so good..
Dude No 2: You know what you need? A nice big glass of TTFU.
de Ashtomus prime 26 août 2007
Acronym for "Tighten The Fuck Up"

Self-explanatory and coined in Salem, Oregon in late 2004 or early 2005.
Hey, T.T.F.U. you idiot
de Big Felony 15 juin 2007
TTFU stands for "tighten the fuck up" as coined by an Orlando, FL based Guitar Hero champion.
While TTFU has been around for thousands of years and linked to the fall of the Roman empire, " Hey Caesar, TTFU," the term fell out of grace with civil society and only resurfaced when a drunk artists wondering the streets of Miami yelled at a waitress "Yo woman, TTFU, I like my wings HOT!"
"What do you mean you're only bringing 65 beers on the camping trip? TTFU."
de Pappa Cock 5 février 2007
TTFU stands for "tighten the fuck up" as coined by an Orlando, FL based Guitar Hero champion.
While TTFU has been around for thousands of years and linked to the fall of the Roman empire, " Hey Caesar, TTFU," the term fell out of grace with civil society and only resurfaced when a drunk artists wondering the streets of Miami yelled at a waitress "Yo woman, TTFU, I like my wings HOT!"
"What do you mean you're only bring 65 beers on the camping trip? TTFU."
de Pappa Cock 31 janvier 2007
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