Top Definition
The house of smiles is the sexual health clinic, where one goes to get rid of his chlamids that his cheating bitch of an exgirlfriend gave him.

Normal people dont go to the house of smiles its always that grimey girl who you knows going to be 16 with 10 black babies in a council estate.
"FUCKING CHLAMYDIA? now im going to have to go to the house of smiles, again!! FOR FUCKS SAKE!"

"i seen your lass down the house of smiles last wednesday, what i didnt go for a check up i was walking past"

"have you give me anything it burns when i piss?"
de DJLMMYERS 13 juin 2010

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