When your crabs have herpes.
Oh man that dude has a horrid case of derpies.
de LIONwho 28 mars 2011
A universal nickname for that really annoying girl that everyone hates. She could be your clingy ex-girlfriend or the girl in your government class that always asks stupid questions. If she's "Derpy" then chances are that everyone you know can find something they hate about her.
"Dude, derpy showed up at my house yesterday, she's so creepy!"

"Are you talking about that blonde chick with the annoying voice? I hate that chick, she gets on my nerves."
de thedirtydan 17 mai 2013
Looking slightly retarded in a picture
"She looks so derpy with that duck face!"
"That guy looks so derpy in his pictures."
de lilstrudel 27 février 2012
Derpy - a homicidal rapist usually hailing from Hawaii, often with the intentions of slicing off people's penises and jellifying them for their scorpion overlords.
Baron Von Muffington is such a Derpy!
de Boss Nigger. 21 mars 2012
Something that can explain something that is cool or dumb.
1)Man this song is so derpy!
2)Yah, that guy is such a derpy derp!
de Rob 17 juin 2004
To be inefficient, slow, unable, inexperienced, not working correctly, stupid, naive, etc. A word that usually takes the place of "retarded."

Can be pertaining to a person or a thing.
I tried to send my essay in via email last night, but my computer was being derpy.

*Friend trips and falls over own feet
You are so derpy sometimes
de Derpyhoovs 27 juillet 2011

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